Eliminating the need for repeat surgeries
In approximately 30% of cancer surgeries, pathology confirms that the tumor was not extracted with clean margins. This means that cancer cells were left behind and the patient may need to undergo a second surgery. Lumicell aims to change this by empowering surgeons to see and remove all cancer cells during the initial surgery, thereby eliminating the need for repeat surgeries, improving surgical outcomes, and reducing healthcare costs.
Lumicell illuminates cancer and other diseased tissues at the molecular level, enabling physicians to take action in real-time during surgeries to improve patient outcomes.
The company’s lead product, the Lumicell System, is in late-stage development for breast cancer surgery, and is also under investigation for ovarian, prostate, brain, colorectal, esophageal, and pancreatic cancers. It features an investigational onco-fluorescent agent and a handheld device that enable cancer surgeons to see and remove cancer cells in real-time during operations.
The Lumicell System was designed and developed by MIT engineers in partnership with leading breast cancer surgeons to fit seamlessly within the existing surgical workflow. The imaging agents and devices are optimized for the specific cancer-type and surgical procedure. The imager technology is based upon a novel imaging concept developed by W. David Lee while he was a member of the David H. Koch Institute for Integrative Cancer Research at MIT and a group of scientists, engineers, and clinicians from MIT and Duke University Medical Center. The proprietary molecular imaging agent was developed by Lumicell and is specifically designed to fluoresce when in or near cancer cells at the tumor margin during surgical resection of the tumor.
The following video demonstrates the use of the Lumicell System during lumpectomy for Intraoperative Detection of Residual Cancer. This procedure was performed by Dr. Barbara Smith as part of a clinical trial NCT03321929 at Mass General Hospital. Please review our disclaimer regarding this video.